Loop electrosurgical excision procedure in Greek patients with vaginal intraepithelial neoplasia

Objective: The aim of our study was to evaluate the therapeutic effectiveness of loop electrosurgical excision procedure (LEEP) in Greek patients with vaginal intraepithelial neoplasia (VAIN).
Materials and Methods: Between January 2002 and January 2009, about 23 women with histologically confirmed VAIN were included in our study. For LEEP procedure we used a high frequency Electrosurgery Unit with at least 80 W output.
Results: Complete response rate, at 12 months of follow up, was 86.96%. Recurrence rate, at 12 months of follow up, was 13.04%. Complete response rate, at 24 months of follow up, was 75%. Recurrence rate, at 24 months of follow up, was 25%.
Conclusion: LEEP may constitute a valuable excisional method for the treatment of VAIN. It provides an interpretable specimen of the whole lesion within a few minutes. It needs a short period of training and has low cost.