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Published February 6, 2022 | Version v1.0.0
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Multi-lens Neural Machine (MLNM)

  • 1. Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore

Description

This repository is the official implementation of the paper: An AI-assisted Tool For Efficient Prostate Cancer Diagnosis.

It uses the data: Digital Pathology Dataset for Prostate Cancer Diagnosis.

We developed a multi-lens (or multi-resolution) deep learning pipeline detecting malignant glands in core needle biopsies of low-grade prostate cancer to assist pathologists in diagnosis. The pipeline consisted of two stages: the gland segmentation model detected the glands within the sections and the multi-lens model classified each detected gland into benign vs. malignant. The multi-lens model exploited both morphology information (of nuclei and glands from high resolution images - 40× and 20×) and neighborhood information (for architectural patterns from low resolution images - 10× and 5×), important in prostate gland classification.

Notes

This study was funded by the Biomedical Research Council of the Agency for Science, Technology and Research, Singapore.

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