Neurodevelopmental outcome of preterm very low birth weight infants admitted to an Italian tertiary center over an 11-year period
- Longo Stefania1
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Caporali Camilla2
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Pisoni Camilla1
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Borghesi Alessandro1
- Perotti Gianfranco1
- Tritto Giovanna3
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Olivieri Ivana4
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La Piana Roberta5
- Tonduti Davide6
- Decio Alice6
- Ariaudo Giada7
- Spairani Silvia7
- Naboni Cecilia8
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Gardella Barbara9
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Spinillo Arsenio9
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Manzoni Federica10
- Tinelli Carmine11
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Stronati Mauro1
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Orcesi Simona7
- 1. IRCCS Policlinico San Matteo Pavia (Italy)
- 2. University of Pavia (Italy), IRCCS Mondino Foundation Pavia (Italy)
- 3. University of Pavia (Italy), Fondazione Stella Maris Mediterraneo Potenza (Italy)
- 4. University of Pavia (Italy), IRCCS Fondazione Don Carlo Gnocchi Milan (Italy)
- 5. University of Pavia (Italy), Montreal Neurological Institute McGill University (Canada)
- 6. University of Pavia (Italy)
- 7. University of Pavia (Italy), IRCCS Mondino Foundation Pavia (Italy)
- 8. IRCCS Mondino Foundation Pavia (Italy)
- 9. IRCCS Foundation Policlinico San Matteo Pavia (Italy), University of Pavia (Italy)
- 10. Health Protection Agency Pavia (Italy), IRCCS Policlinico San Matteo Foundation Pavia (Italy)
- 11. IRCCS Policlinico San Matteo Foundation Pavia (Italy)
Description
This database includes the raw data linked with the paper “Neurodevelopmental outcome of preterm very low birth weight infants admitted to an Italian tertiary center over an 11-year period”.
In this paper, we reported the data of perinatal history and neurodevelopmental outcome of a single center cohort of Italian preterm VLBWi born between 2005 and 2015.
The aim of the study is to describe neurodevelopmental outcome at 24 months of corrected age and to identify associations between perinatal risk factors and neurodevelopmental outcome.
502 VLBWi completed the follow up. 75.3% showed a normal outcome, 13.9% minor sequelae and 10.8% major sequelae (3.8% cerebral palsy). Male gender (OR 1.59 CI 95% 1.0-2.5 p value 0.043), bronchopulmonary dysplasia (OR 1.7 CI 95% 1.1-2.9 p value 0.026), abnormal neonatal neurological assessment (OR 2.1 CI 95% 1.3-3.4 p value 0.002) and severe brain ultrasound abnormalities (OR 6.1 IC 95% 2.4-15.1 p value <0.001) were independently associated with poor outcome on multivariate ordered logistic regression.
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Related works
- Is published in
- Journal article: 10.1038/s41598-021-95864-0 (DOI)