The Demonstration of Spontaneous Self-assembly of Novel Fluorescent Pro flavin-Lipids
Description
Biomolecular Research Unit, Regional Research Laboratory (CSIR), Trivandrum-695 019 Cental Drug Research Institute, Lucknow-226 001
Centre for Cellular and Molecular Biology, Hyderabad
Manuscript received 27 July 1998
Fluorescent quaternary salts derived from proflavin (Pf) harbouring long alkyl chains, organize into unilamellar bilayer vesicles of diameter 22-28 nm in water and form mixed liposomes with egg lecithin lipids. The DNA binding capability of Pf-lipids and their liposome preparations have been demonstrated by fluorescence spectroscopic studies.