Data Integration to Identify and Prioritize Potential Regulatory Variants for Rheumatoid Arthritis in a Post-GWAS era

Jahangir, SIdrah

doi:10.5281/zenodo.5913313

Published January 28, 2022 | Version v1

Dataset Open

Data Integration to Identify and Prioritize Potential Regulatory Variants for Rheumatoid Arthritis in a Post-GWAS era

Jahangir, SIdrah¹

1. National University of Sciences aandTechnology

The Data set contain data related to the SNPs in linkage disequilibrium with published GWAS rheumatoid arthritis SNPs and the subsequent annotation and pathway analysis files performed to identify putative 'missed' variants of rheumatoid arthritis.

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Annotation data of the query SNPs and proxy SNPs with RegulomeDB score 3.docx md5:98de2a82464d67bd5e88bbaff9f83dc7	66.4 kB	Download
Expression quantitative trait loci (QTLs) whose expression was altered by the SNPs with RegulomeDB score 3 along with the SNPs that control their expression.docx md5:9721e7972167d3fce67796eed9c9d35b	52.5 kB	Download
Functional classification of the genes expressed by linked eQTLs using Gene List Analysis tool provided by PANTHER14.1..docx md5:7f64424d7b72ed0105e3525e35cd5368	19.4 kB	Download
GWAS significant rheumatoid arthritis SNPs used as query SNPs for search of proxy variants.docx md5:766c8698500c005ba761a14cc251db07	720.4 kB	Download
KEGG pathways associated with 13 hub proteins expressed by hub expression quantitative trait loci (eQTLs).docx md5:1ad14d2e765121a7116f3b97a43570bc	16.3 kB	Download
List of SNPs retrieved from SNiPA proxy search tool at threshold 0.8 alongwith their chromosomal co-ordinates and Regulome DB scores.xls md5:1138d92c6d3306b0f16679216324b861	1.1 MB	Download
SNPfunc and RegulomeDB annotation data (protein binding and motifs) of the novel candidate SNPs for RA.docx md5:2989810f6838636540f581f899d28697	20.3 kB	Download

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Data Integration to Identify and Prioritize Potential Regulatory Variants for Rheumatoid Arthritis in a Post-GWAS era

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