Calliphyllin, a New Diterpene from the Leaves of Callicarpa macrophylla

Centre of Advanced Studies on Natural Products, Department of Chemistry, University College of Science, Calcutta-700 009
Manuscript received March 31, 1994

A new diterpene designated calliphyllin, betulinic acid, 5,4'-dihydroxy-3,7,3'-trimethoxyflavone, 5,4'-dihydroxy-3,7-dimethoxyflavone and β-sitosterol have been isolated from the leaves of Callicarpa macrophylla Vahl. (Verbenaceae). Calliphyllin has been shown to possess 14α-hydroxy-isopimaric acid (1) structure on the basis of nmr and mass spectral and chemical evidence.