FONDAZIONE IRCCS ISTITUTO NEUROLOGICO "CARLO BESTA"
Published January 20, 2022 | Version v1
Dataset Restricted

Dataset related to article "Peripheral blood mononuclear cell activation sustains seizure activity"

Authors/Creators

  • 1. Fondazione IRCCS Istituto Neurologico Carlo Besta

Description

Emerging data propose innate and adaptive immune cells as possible triggers of ictogenesis. Activated immune cells induce blood-brain barrier (BBB) permeability changes responsible for the extravasation into the brain parenchyma of serum proteins and other inflammatory mediators that promote neuroinflammation and seizures.The identification of cellular and soluble biomarkers that describe these processes is mandatory to better understand dysimmune encephalopathies with seizures.

Notes

Funding: Fondazione Epilessia LICE - grant 2019; European Union's Horizon 2020 Research and Innovation Programme under the Marie Sklodowska-Curie grant agreement no. 722053 (EU-GliaPhD), Italian Health Ministry, EPICARE project of the Associazione Paolo Zorzi per le Neuroscienze, FISM – Fondazione Italiana Sclerosi Multipla – cod. 2019/R-Single/065.

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Additional details

Related works

Is supplement to
Journal article: 10.1111/epi.16935. (DOI)

Funding

European Commission
EU-GliaPhD - Training, Research and Raising of Public Awareness in Cell Biology and Pathology of Neuroglia 722053