Spectrophotometric determination of cadmium(II) using novel oxime-hydrazones in biological materials

Department of Chemistry, JNTU College of Engineering, Anantapur-515 001, India

Department of Chemistry, Sri Krishnadevaraya University, Anantapur-515 003, India

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Manuscript received 22 May 2000, revised 17 January 2001, accepted 10 February 2001

The analytical characteristics of three new oxime-hydrazones are described. The reagents diacetylmonoxime benzoylhydrazone (DMBH), diacetylmonoxime isonicotinoylhydrazone (DMIH) and benzil-α-monoxime isonicotinoylhydrazone (BMIH) give yel­low coloured solutions with cadmium(II) in borate buffers. The molar absorptivity and Sandell's sensitivity of Cd^II-DMBH, Cd^II-DMIH and Cd^II-BMIH are 1.6 x 10⁴, 2.0 x 10⁴ and 2.5 x 10⁴ dm³ mol^-1 cm^-1 at 348, 346 and 362 nm, and 0.00712, 0.00562 and 0.00450 µg cm^-2, respectively. BMIH has been used for the spectrophotometric determination of cadmium(II) in some biological samples.