ORGANOPHOSPHORUS COMPOUNDS CONTAINING 3-(SUBSTITUTED PHENYL)- 2-THIOXOIMIDAZOLIDIN-4-ONE AS POTENT ANTIMICROBIAL AGENTS

A series of biologically active organophosphorus compounds have been synthesized by the reactions of 4-Chlorophenyl dichlorophosphate with 3-(substitutedphenyl)-2-thioxoimidazolidin-4-one. The compounds have been characterized on the basis of elemental analyses and spectral (IR, ¹H NMR ³¹P NMR) data. All the compounds were screened for their antimicrobial activity .They were found to possess significant anti-microbial activity.