Synthesis and antibacterial activity of 4-arylazo-1-substituted- 3,5-diphenylpyrazoles

Department of Pharmaceutical Chemistry, Hamdard University, Hamdard Nagar, New Delhi-11 0 062

E-mail : amirs@vsnl.net

Manuscript received 27 April 200/, revised 30 July 2001, accepted 17 August 2001

Various 4-arylazo-1-(2-acetonaphthyl)-3,5-diphenyl pyrazoles (2a-g), 4-arylazo-1-isonicotinyl-3,5-diphenyl pyrazoles (3a-g) and 4-arylazo-1-thiocarbamoyl-3,5-diphenylpyrazoles (4a-g) have been synthesized and evaluated for their antibacterial activity. The compounds show significant antibacterial activity.