Recent advances in research on antituberculars

Lupin Limited, 159 CST Road, Kalina, Santacruz (East), Mumbai-400 098, India
E-mail: bnroy@lupinindia.com
Manuscript received 8 Marcl1 2001, revised 20 August 2001, accepted 23 August 2001

Alarming rise in the incidence of tuberculosis cases worldwide has made an infectious disease like tuberculosis, one of the top priorities on World Health Organization's agenda. Although, a variety of new antibacterial compounds are becoming available for fighting a number of infectious diseases, antitubercular drugs do not form a part of It, perhaps owing to the perception of it being not so-lucrative market opportunity, coupled with complexity of the research involved in finding new anti-TB drugs. The present article is Intended to highlight the current therapy available to combat TB and to focus on research that is being carried out at various laboratories for finding out potent new therapeutics and to highlight the lead compounds emerging from these efforts.