Synthesis of some new 2-mercaptobenzothiazolyl-2-oxoazetidines as antimicrobial and anthelmintic agents

Synthetic Organic Chemistry Laboratory, Chemistry Department, Dr. H. S. Gour University, Sagar-470 003, India

E-mail : professorsks@rediffmail.com

Manuscript received 31 January 2003, revised 14 August 2003, accepted 30 October 2003

Several 2-(arylidenylamino)-5-[{2-benzothiazolylthio)methyl]-1 ,3,4-thiad iazoles (4) and 1-[5'- {(2- benzothiazolylthio)methyl }-1 ,3,4-thiadiazol-2' -yl]-4-substituted-3-chloro-2-oxoazetid ines (5) have been synthesized and tested for their antibacterial, antifungal and anthelmintic activities. Structure of the compounds have been elucidated on the basis of their elemental analyses and spectral data.