Microwave assisted Knoevenagel condensation : A facile method for the synthesis of 5-arylidine barbituric acid derivatives under solvent free conditions†

P. G. and Research Center, Department of Chemistry, Padmashri Vikhe Patil College, Pravaranagar (Loni kd.), Tal. Rahata, Dist. Ahmednagar-413 713, Maharashtra, India

E-mail: akankshapandit2002@yahoo.com

Manuscript received 22 June 2006, revised 14 June 2007, accepted 20 July 2007

Several benzoldehydes were condensed with barbituric acid under microwave irradiation in absence of solvent affording the corresponding 5-arylidine barbituric acid derivatives in short reaction period with high yields.