Mauritine-K, A new antifungal cyclopeptide alkaloid from Zizyphus mauritiana

Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221 005,
Uttar Pradesh, India
E-mail: pandeyvb@sify.com Fax: 91-542-2367568
Department of Chemistry, S. G. R. P. G. College, Dobhi-222 149, Purvanchal University, Jaunpur, Uttar Pradesh, India
Manuscript received 19 August 2006, revised 19 April 2007, accepted 13 June 2007

The cyclopeptide alkaloids, mauritine-K and sativanine-K have been isolated from the root bark of Zizyphus mauritiana and their structures established by spectral and chemical evidences. Mauritine-K is a new cyclopeptide alkaloid and sativanine-K is the first report from Z. mauritiana. Mauritine-K exhibited significant antifungal activity.