Monitoring feedback to authors on the quality of trials evaluating interventions aimed at preventing and treating COVID-19

We aimed to assess transparency of reporting and risk of bias of randomized trials evaluating interventions aimed at preventing and treating COVID-19.

This review is part of a larger project: the COVID-NMA project (Boutron 2020a). The COVID-NMA project aims to provide decision-makers with a complete, high-quality and up-to-date synthesis of evidence on interventions for the prevention and treatment of COVID 19. For this purpose, we perform a living mapping of all registered randomized controlled trials and a living evidence synthesis of data from RCTs. We developed a master protocol on the effect of all interventions for the prevention and treatment of COVID-19 (first published on April 8, 2020; an update on May 11, 2020, June 17, 2020, and September 8, 2020) (Boutron 2020b). We set-up a platform (https://covid-nma.com) where all our results are made available and updated weekly.