Triterpene constituents and antibacterial activity of the stems of Reissantia grahamii
Description
Department of Chemistry, University College of Science and Technology, 92, Acharya Prafulla Chandra
Road, Kolkata-700 009, India
E-mail : amarendra.patra@gmail.com; sumana2000@rediffmail.com
Department of Biochemistry·, University College of Science, 35, Ballygunge Circular Road,
Kolkata-700 019, India
E-mail : pkbbioc@caluniv.ac.in
Department of Applied Sciences, Higher College of Technology, P.B. 74, P.C. 133, Muscat,
Sultanate of Oman
E-mail : drsuku@yahoo.com
Manuscript received 08 July 2011, accepted 19 September 2011
The stems or the medicinal plant Reissantia grahamii has furnished a new triterpenoid designated reissantiadiol (1) together with friedelin, pachysandiol-A, canophyllol, endodesmiadiol (2) and abruslactone-A (3). Structures 1, 2 and 3 were established from extensive 1D and 2D NMR studies. Preliminary antibacterial activity studies on crude ethyl acetate extract of defatted stems showed strong activity against bacterial strains Escherichia coli strain V (Verotoxigenic E. coli), Staphylococcus aureus, Bacillus subtilis, Vibrio cholerae and Pseudomonas aeruginosa.