Published November 19, 2021 | Version v1

GC-PC_Cerebellar_Connectivity _Maps

  • 1. Institut des Neurosciences Cellulaires et Intégratives, CNRS, Université de Strasbourg, 67084 Strasbourg, France
  • 2. Aix-Marseille Université, Institut de Neurosciences des Systèmes, CNRS, Marseille, France
  • 3. University of Strasbourg Institute for Advanced Studies (USIAS), 67084 Strasbourg, France

Description

Here we provide the dataset (raw electrophysiological recordings + processed data) used to build synaptic maps and compute graph properties in the following article: Cerebellar connectivity maps embody individual adaptive behavior in mice (Spaeth, Bahuguna et al.). 

Just unzip the entire file to find the following elements:


RawData
Electrophysiological recordings were recorded with WinWCP 4.2.2 freeware (John Dempster, SIPBS, University of Strathclyde, UK)

  • Adaptive_Dataset: raw electrophysiological recordings, sorted by individual maps in each adaptive conditions (EC, early cuff; ES, early sham; LC, adapted cuff; LS, adapted sham; ENR, trained; WT, control). Mappings were performed at high-resolution (20*20µm). 
    Experimental info as well as file sorting are noted in the corresponding spreadsheets within the following notebook: Spaeth_Bahuguna_et_al_GCPC_Mappings_Adaptive_High_Res_Info.xlsx 
     
  • Development_Dataset: raw electrophysiological recordings, sorted by individual maps in developmental conditions (P9-P10; P12-P13; P14-P18; >P30). Mappings were performed at low-resolution (40*40µm). 
    Experimental info as well as file sorting are noted in the corresponding spreadsheets within the following notebook: Spaeth_Bahuguna_et_al_GCPC_Mappings_Development_Low_Res_Info.xlsx

 

Processed Data:
Files are saved in .csv format.

  • Adaptive_Dataset: processed synaptic maps, sorted by individual maps in each adaptive conditions (EC, early cuff; ES, early sham; LC, adapted cuff; LS, adapted sham; ENR, trained; WT, control).
    Measures of the Zebrin Bands are found in the following file:
    Spaeth_Bahuguna_et_al_Measures_Zebrin_Adaptive_HighResDataset.xlsx
  • Development_Dataset: processed synaptic maps, sorted by individual maps in each developmental condition (P9-P10; P12-P13; P14-P18; >P30).
    Measures of the Zebrin Bands are found in the following file:
    Spaeth_Bahuguna_et_al_Measures_Zebrins_Development_LowRes_dataset.xlsx

Description of the files (also included in READ_ME.pdf):

  1. XXX_Positions_cp_centered_OK.csv: a vector containing the normalized, relative position along the mediolateral axis for map XXX
  2. XXX_Amp_max_OK.csv: a vector containing the maximal synaptic amplitude (in pA) in each column of map XXX, sorted along the mediolateral axis
  3. XXX_Amp_Noisemap_OK.csv: a matrix containing the synaptic noise (in pA) in site of map XXX
  4. XXX_Amp_Sigma_OK.csv: a matrix containing the standard deviation of the synaptic noise for the entire map XXX (identical value in each cell)
  5. XXX_Amp_zscore_2D_OK.csv: a matrix containing the z-score of each site in map XXX
  6. XXX_Amp_Zscore_max_OK.csv: a vector containing the maximal z-score in each column of map XXX, sorted along the mediolateral axis
  7. XXX_Files_List.csv: a list of the .wcp files used to generate map XXX
  8. XXX_Positions_OK.csv: a vector containing the absolute position along the mediolateral axis for map XXX
  9. XXX_Amp_2D_OK.csv: a matrix containing the average synaptic amplitude (in pA) recorded for each site of map XXX
  10. XXX_Zebrin_OK.csv: a vector containing the relative position of the Zebrin bands for map XXX

 

Files

SpaethBahugunaData.zip

Files (26.4 GB)

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md5:2f32afc6e8b09dd269d3f178ecc55b5a
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Additional details

Funding

Agence Nationale de la Recherche
NetOnTime - Specific wiring rules implicate diverse temporal processing within cerebellar microcircuits ANR-19-CE16-0019
Agence Nationale de la Recherche
CeMod - Modular information processing in the cerebellum and movement disorders ANR-15-CE37-0001
Agence Nationale de la Recherche
SENCE - Movement disorders in Parkinson’s disease: The role of somatosensory deficits and cerebellar anomalies ANR-18-CE37-0018
Agence Nationale de la Recherche
MultiMod - Multi-modular Basis of Motor Adaptation and Learning ANR-19-CE37-0007