Published November 15, 2021 | Version v1
Dataset Open

Summary statistics from "Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease"

Creators

  • 1. IMISE, Universtiy Leipzig

Description

GWAMA summary statistics of four steroid hormone levels using fixed-effect model and GWAS summary statistics of four other steroid hormones.

When using this data, please cite: Pott J, Bae YJ, Horn K, et al.. Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 2019 Nov 1;104(11):5008-5023. doi: 10.1210/jc.2019-00757

All txt files contain the following columns:

  • markername
  • chr
  • bp_hg19 (base position according to hg19)
  • effect_allele
  • other_allele
  • effect_allele_freq
  • min_info (minimal info score across all used studies)
  • n (sample size per SNP)
  • beta (effect estimate)
  • se (standard error)
  • p (p-value)
  • CochransQ (only in GWAMA; SNP heterogeneity across studies)
  • pCochransQ (only in GWAMA; p-value of Cochrans Q value)

Files

SummaryStatisticsALDO.zip

Files (7.3 GB)

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Additional details

References

  • Pott J, Bae YJ, Horn K, Teren A, Kühnapfel A, Kirsten H, Ceglarek U, Loeffler M, Thiery J, Kratzsch J, Scholz M. Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab. 2019 Nov 1;104(11):5008-5023. doi: 10.1210/jc.2019-00757. PMID: 31169883