Published November 5, 2021 | Version v1

Solvent sites detection from molecular dynamics in mixed solvents

Authors/Creators

  • 1. Faculty of Exact and Natural Sciences, University of Buenos Aires

Description

In this zip file, you will find 3 molecular dynamics (MDs) that were run using the AMBER molecular dynamics package (https://ambermd.org/), and the necessary scripts to obtain the solvent sites.

The MDs correspond to the kinase and rubredoxin domains of protein kinase G from Mycobacterium tuberculosis. 

 

 

Files

pkngSolventsSiteDetectionAmber.zip

Files (1.4 GB)

Name Size
md5:0a4f1e9a3afcb32627ad15cdf569d492
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Additional details

References

  • Arcon, Juan Pablo, et al. "Molecular dynamics in mixed solvents reveals protein–ligand interactions, improves docking, and allows accurate binding free energy predictions." Journal of chemical information and modeling 57.4 (2017): 846-863.