Published November 2, 2021 | Version 0.1
Dataset Open

Dataset variants used in "Task-Driven Knowledge Graph Filtering Improves Prioritizing Drugs for Repurposing"

Authors/Creators

  • 1. Helmholtz Zentrum München

Description

This file contains all datasets and variants thereof used in the linked paper. We do not take credit for constructing the datasets, which has been done by the respective original authors (https://github.com/hetio/hetionet, https://github.com/gnn4dr/DRKG). For our work we produced modified versions (called "subset" in the file) by applying our metapath based filtering approach. For validation purposed we also constructed ablation versions where one specific type of entities is missing (i.e. "nogene", "noside", etc).

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Additional details

Related works

Is supplement to
Preprint: 10.21203/rs.3.rs-721705/v1 (DOI)

References

  • Ioannidis et al., 2020. DRKG - Drug Repurposing Knowledge Graph for Covid-19. https://github.com/gnn4dr/DRKG/
  • Himmelstein et al., 2017. Systematic integration of biomedical knowledge prioritizes drugs for repurposing. eLife 2017;6:e26726 DOI: 10.7554/eLife.26726