Published March 31, 2021 | Version v5

Analysis of Multiple Sclerosis using Serum level of vitamin D

Authors/Creators

  • 1. Department of Neurology, School of Medicine, University of Medical Sciences, Taiwan

Description

Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous
system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and
causes communication problems between your brain and the rest of your body. Eventually, the disease can
cause permanent damage or deterioration of the nerves. Research over the years has shown that maintaining
adequate levels of vitamin D may have a protective effect and lower the risk of developing multiple
sclerosis (MS). A number of studies have shown that people who get more sun exposure and vitamin D in
their diet have a lower risk of MS. Therefore, vitamin D supplementation is considered an important
modifiable environmental risk factor for development of multiple sclerosis
50 newly diagnosed MS patients and 30 healthy counterparts who were the relatives of the patients were
studied in two groups of case and control. The two groups were matched in terms of age, sex, time of
sampling, shelter and nutrition. Serum levels of vitamin D, parathyroid hormone, calcium and phosphorus,
was measured, recorded and analyzed.
The mean level of vitamin D in the case and control groups was respectively 27.33 and 27.98 ng/dl. The
mean of PTH in the case group of 65.6 ng/dl. In the control group is 62.1 ng/dl. also during the study of
serum level of calcium with an average of 9.17 ng/dl in the case group s and the average of 9.41 ng/dl in the
control group, serum phosphate level with an average of ng/dl 3.59 and 3.37 ng/dl, respectively were
calculated in case and control groups that was not showed a significant difference.
 

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Additional details

Related works

Is cited by
Journal article: 10.5281/zenodo.5564105 (DOI)

Subjects

biotechnology
10.5281/zenodo.5564105