Supplementary data --The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA supertype-dependent manner
Authors/Creators
- 1. University of Montreal, Centre Hospitalier Universitaire Sainte-Justine
Description
Supplementary data for the Cell Systems manuscript 'The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA supertype-dependent manner', by Hamelin et al.
GISAID_Authors_Recognition_2021-01-19. Metadata concerning the SARS-CoV-2 viral sequences analysed, and generously provided by GISAID.
Table S1. SARS-CoV-2 mutations identified from 330,246 GISAID entries (December 31st 2020), Related to Figure 1 and Figure 2. SARS-CoV-2 mutations at the nucleic and amino acid level are indicated. Number of genomes carrying mutation show the frequency of individual mutations among all SARS-CoV-2 variants.
Table S2. SARS-CoV-2 prevalent mutations identified from 330,246 GISAID entries (December 31st 2020) and detected in at least 100 individuals, Related to Figure 2.
Table S3. Previously validated SARS-CoV-2 CD8+ T cell epitopes and their matching mutated forms identified in this study, Related to Figure 1 and Figure 2.
Table S4. List of previously validated SARS-CoV-2 CD8+ T cell epitopes. Epitopes were downloaded from https://www.mckayspcb.com/SARS2TcellEpitopes/ (as of January 2021). This database has effectively catalogued all SARS-CoV-2 CD8+ epitopes validated by 18 separate studies. See Quadeer et al. 2021 for details, Related to Figure 1 and Figure 2.