Dataset Open Access

Bioenergetic cluster analysis – mitochondrial respiratory control in human fibroblasts

Gnaiger, Erich

Gnaiger E (2021) Bioenergetic cluster analysis – mitochondrial respiratory control in human fibroblasts. MitoFit Preprints 2021.8. doi:10.26124/mitofit:2021-0008 - https://www.mitofit.org/index.php/Gnaiger_2021_MitoFit_BCA

All respirometric data that were used for meta-analysis are obtained from the original publications, were converted to SI units, and are available here as a basis for bioenergetic cluster analysis. Inverted regression analysis is illustrated by an example (Figures 1c and d).

This work was partially funded by the European Union's Horizon 2020 research and innovation programme under grant agreement No. 859770, NextGen-O2k project.
Files (1.7 MB)
Name Size
BCA_Greco_2003_FEBS J_Zenodo.xlsx
md5:336733dcceac576c1cb871c7f0cd9879
26.1 kB Download
BCA_Hutter_2004_Biochem J_Zenodo.xlsx
md5:81dedeb075d8011ff9e21a9715172176
26.2 kB Download
BCA_Jepez_2018_PLOS ONE_Zenodo.xlsx
md5:78ec34081264c69b96d2636040bd95ac
1.6 MB Download
BCA_Zdrazilova_2021_MitoFit_ace-sce_Zenodo.xlsx
md5:1546036dd517f5d217640a6db911cf13
19.3 kB Download
Inverted regression analysis_Zenodo.xlsx
md5:66086eb965fa47dd610fd9315f564372
37.7 kB Download
  • Gnaiger E (2021) Bioenergetic cluster analysis – mitochondrial respiratory control in human fibroblasts. MitoFit Preprints 2021.8. doi:10.26124/mitofit:2021-0008 - https://www.mitofit.org/index.php/Gnaiger_2021_MitoFit_BCA

  • Greco M, Villani G, Mazzucchelli F, Bresolin N, Papa S, Attardi G (2003) Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts. FASEB J 17:1706-8.

  • Hütter E, Renner K, Pfister G, Stöckl P, Jansen-Dürr P, Gnaiger E (2004) Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts. Biochem J 380:919-28.

  • Yépez VA, Kremer LS, Iuso A, Gusic M, Kopajtich R, Koňaříková E, Nadel A, Wachutka L, Prokisch H, Gagneur J (2018) OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer. PLOS ONE 13:e0199938. https:// doi.org/10.1371/journal.pone.0199938

  • Zdrazilova L, Hanskova H, Gnaiger E (2021) Comparable respiratory activity in attached and suspended fibroblasts. MitoFit Preprints 2021.7. doi:10.26124/mitofit:2021-0007

55
30
views
downloads
All versions This version
Views 5540
Downloads 3020
Data volume 8.5 MB5.2 MB
Unique views 4033
Unique downloads 1410

Share

Cite as