Published June 30, 2015
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First Total Synthesis of Pandamarine
- 1. University of Crete
Description
The first total synthesis of pandamarine, an alkaloid isolated from Pandanus amaryllifolius is reported. The key step of this extremely short (six steps in total) and protecting group-free synthesis is a highly efficient cascade reaction sequence initiated by the photooxidation of an easily accessible and symmetric difuran precursor.
Notes
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see: http://pubs.acs.org/page/policy/articlesonrequest/index.html
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