Published June 30, 2016 | Version 1.0
Dataset Open

FlyCircuit Dotprops

Creators

  • 1. Department of Zoology, University of Cambridge, UK
  • 2. MRC Laboratory of Molecular Biology, Cambridge, UK

Description

Dotprops for FlyCircuit neurons published in Costa et al. (2016).

In brief, ~16k confocal images from the FlyCircuit dataset (Chiang et al., 2011) were registered (Jefferis et al., 2007) to an intersex template brain (FCWB, Costa et al. 2016), skeletonised and converted to dotprops using the R package nat (Bates et al., 2020). Dotprops represent neurons as points with associated tangent vectors (i.e. local headings). See Costa et al. (2016) for further details.

Contents:

  • flycircuit_dotprops.zip contains 16,129 dotprops as individual CSV files. File names correspond to FlyCircuit gene names. Units are in microns and neurons are in FCWB (FlyCircuit Whole Brain) template space.
  • meta.csv contains a mapping between FlyCircuit gene and neuron names, and an integer identifier.

See also nat.flycircuit for ready access to these dotprops and additional meta data. 

Files

flycircuit_dotprops.zip

Files (848.2 MB)

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Additional details

References

  • Costa et al. "NBLAST: Rapid, Sensitive Comparison of Neuronal Structure and Construction of Neuron Family Databases." Neuron vol. 91,2 (2016): 293-311. doi:10.1016/j.neuron.2016.06.012
  • Chiang et al. "Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolution." Current biology : CB vol. 21,1 (2011): 1-11. doi:10.1016/j.cub.2010.11.056
  • Bates et al. "The natverse, a versatile toolbox for combining and analysing neuroanatomical data." eLife vol. 9 e53350. 14 Apr. 2020, doi:10.7554/eLife.53350
  • Jefferis et al. "Comprehensive maps of Drosophila higher olfactory centers: spatially segregated fruit and pheromone representation." Cell vol. 128,6 (2007): 1187-203. doi:10.1016/j.cell.2007.01.040