Peripheral artery disease: how much inter-leg symmetry? A contrast-enhanced magnetic resonance angiography study
Authors/Creators
- 1. Unit Of Radiology, Irccs Policlinico San Donato.
- 2. Unit Of Radiology, Irccs Policlinico San Donato
- 3. Unit of Diagnostic Imaging and Stereotactic Radiosurgery, CDI Centro Diagnostico Italiano, Via Saint Bon 20, Milan.
- 4. Postgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, Milan, Italy.
- 5. Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Morandi 30, San Donato Milanese.
Description
Dataset from the article Secchi F, Di Leo G, Delnevo A, Alì M, D'Angelo ID, Nardella VG, Sardanelli F. Peripheral artery disease: how much inter-leg symmetry? A contrast-enhanced magnetic resonance angiography study. Medicine (Baltimore). 2020 Apr;99(16):e19637. doi: 10.1097/MD.0000000000019637. PMID: 32311934; PMCID: PMC7220080.
Abstract
The aim of this observational retrospective study was to qualitatively and quantitatively evaluate the symmetry of atherosclerotic plaques in patients with peripheral artery disease (PAD) undergoing contrast-enhanced magnetic resonance angiography of lower limbs. We retrospectively evaluated the peripheral magnetic resonance angiography of 82 patients considering the iliac, femoral and tibial arteries. Stenosis was scored 0 (none), 1 (<50%), 2 (50%-74%), 3 (75%-99%), and 4 (occluded). Symmetry was quantified as the percentage of bilaterally-diseased arteries and using the inter-leg absolute score difference (0-4). Signs test and Cohen κ were also calculated. Seventy-one (87%) patients had ≥1 bilaterally-diseased artery, and 168 (20%) of 820 artery pairs were bilaterally affected. At least 1 bilateral stenosis was observed from 11% (right internal iliac) to 73% (right superficial femoral). All 10 arteries showed symmetry, none of the inter-leg comparisons being significantly different (P ≥ .100). Cohen κ ranged from 0.208 (common femoral) to 0.533 (internal iliac). This study showed that PAD was symmetrically distributed between the 2 legs, with the internal iliac artery being the most symmetric segment. Symmetry of PAD was quantified in 20%.
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