Computational Fluid Dynamics Modeling of Proximal Landing Zones for Thoracic Endovascular Aortic Repair in the Bovine Arch Variant.
Authors/Creators
- 1. Cardiovascular Department, Clinical Research Unit, IRCCS - Policlinico San Donato, Milan, Italy; Cardiovascular Department, Vascular Surgery Unit, IRCCS - Policlinico San Donato, Milan, Italy. Electronic address: massimiliano.marroccotrischitta@grupposandonato.it.
- 2. 3D and Computer Simulation Laboratory, IRCCS - Policlinico San Donato, Milan, Italy.
- 3. Cardiovascular Department, Clinical Research Unit, IRCCS - Policlinico San Donato, Milan, Italy.
- 4. Minimally Invasive Cardiac Surgery Unit, Istituto Clinico Sant'Ambrogio, Milan, Italy.
- 5. Cardiovascular Department, Vascular Surgery Unit, IRCCS - Policlinico San Donato, Milan, Italy; Department of Scienze Biomediche per la Salute, University of Milan, Milan, Italy.
Description
Dataset from the article Marrocco-Trischitta MM, Romarowski RM, Alaidroos M, Sturla F, Glauber M, Nano G. Computational Fluid Dynamics Modeling of Proximal Landing Zones for Thoracic Endovascular Aortic Repair in the Bovine Arch Variant. Ann Vasc Surg. 2020 Nov;69:413-417. doi: 10.1016/j.avsg.2020.05.024. Epub 2020 May 29. PMID: 32479874.
Abstract
Background: To assess the endograft displacement forces (DF), which quantify the forces exerted by the pulsatile blood flow on the vessel wall and transmitted on the terminal fixation site of the endograft after its deployment in proximal landing zones (PLZs) of the bovine aortic arch variant.
Methods: Thirty healthy aortic computed tomographic angiographies of subjects with bovine arch configuration (10 per type of arch, I-III) were selected for the purpose of the study. A 3-dimensional model of the aortic arch lumen was reconstructed. Computational fluid dynamics modeling was then used to compute DF magnitude and orientation (i.e., x, y, and z axes) in PLZs of each case. DF values were normalized to the corresponding aortic wall area to estimate equivalent surface traction (EST).
Results: DF were highest in zone 0, consistently with the greater surface area. DF in zone 3 were much greater than in zone 2 because of a 3-fold greater upward component (z axis) (P < 0.001), being therefore mainly oriented orthogonally to the aortic blood flow and to the vessel longitudinal axis in that zone. EST progressively increased from zone 0 toward more distal PLZs, with EST in zone 3 being much greater than that in zone 2 (P < 0.001). The same pattern was observed after stratification by type of arch.
Conclusions: The bovine arch is associated with a consistent fluid dynamic pattern, which identifies in zone 3 an unfavorable biomechanical environment for endograft deployment.
Files
Restricted
The record is publicly accessible, but files are restricted. <a href="https://zenodo.org/account/settings/login?next=https://zenodo.org/records/5140792">Log in</a> to check if you have access.
Request access
If you would like to request access to these files, please fill out the form below.
You need to satisfy these conditions in order for this request to be accepted:
These data are available upon duly motivated request to the corresponding author of the article
You are currently not logged in. Do you have an account? Log in here