Published July 25, 2021
| Version 2.0.0
Dataset
Open
Parameter estimation data repository - "Spatial discordances between mRNAs and proteins in the intestinal epithelium"
Creators
- 1. Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
- 2. The De Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot 7610001, Israel
- 3. Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 7610001, Israel
- 4. Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland
Description
The repository contains data associated with the estimation of protein translation and decay rates in the manuscript "Spatial discordances between mRNAs and proteins in the intestinal epithelium". Specifically, it includes MCMC-chains approximating the posterior parameter distribution and figures showing the model's fit to the data for each gene as well as a summary table of all fit results for two different models, the constant translation-rate model ("constant_rate_model") and the declining translation-rate model ("declining_rate_model") as explained in the manuscript.
Code associated with the parameter estimation is available at https://github.com/LiBuchauer/spatial_MP_discordances .