Published June 11, 2021 | Version v1

Increased functional connectivity of the intraparietal sulcus underlies the attenuation of numerosity estimations for self-generated words

  • 1. Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), CH-1202 Geneva, Switzerland ; Brain Mind Institute, Faculty of Life Sciences, Swiss Federal Institute of Technology (EPFL), CH-1015 Lausanne, Switzerland
  • 2. Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), CH-1202 Geneva, Switzerland; Brain Mind Institute, Faculty of Life Sciences, Swiss Federal Institute of Technology (EPFL), CH-1015 Lausanne, Switzerland; Univ. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, LPNC, 38000 Grenoble, France
  • 3. Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), CH-1202 Geneva, Switzerland; Brain Mind Institute, Faculty of Life Sciences, Swiss Federal Institute of Technology (EPFL), CH-1015 Lausanne, Switzerland; Department of Neurology, University of Geneva, CH-1211 Geneva, Switzerland

Description

Description of the dataset:

Healthy participants imaging data (N=25). Data set includes MPRAGE, field map and 3 runs of task fMRI.

Data is organized in BIDS format. Nifti zipped files are uploaded together with corresponding json and tsv files describing the sequence and task events.

json files describing the study sample and details of the task are included.

Abstract of the study:

Previous studies have shown that self-generated stimuli in auditory, visual, and somatosensory domains are attenuated, producing decreased behavioral and neural responses compared to the same stimuli that are externally generated. Yet, whether such attenuation also occurs for higher-level cognitive functions beyond sensorimotor processing remains unknown. In this study, we assessed whether cognitive functions such as numerosity estimations are subject to attenuation in 56 healthy participants (32 women). We designed a task allowing the controlled comparison of numerosity estimations for self (active condition) and externally (passive condition) generated words. Our behavioral results showed a larger underestimation of self- compared to externally-generated words, suggesting that numerosity estimations for self-generated words are attenuated. Moreover, the linear relationship between the reported and actual number of words was stronger for self-generated words, although the ability to track errors about numerosity estimations was similar across conditions. Neuroimaging results revealed that numerosity underestimation involved increased functional connectivity between the right intraparietal sulcus and an extended network (bilateral supplementary motor area, left inferior parietal lobule and left superior temporal gyrus) when estimating the number of self vs. externally generated words. We interpret our results in light of two models of attenuation and discuss their perceptual versus cognitive origins.

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