Published June 3, 2021 | Version v1.1

Input files for simulation of potassium channels using the AMOEBA polarizable force field

  • 1. University of Texas at Austin

Description

This dataset contains input Tinker xyz and key files for the simulation of KcsA potassium channels in DOPC bilayer, a simple script for converting CHARMM pdb file to Tinker xyz file, and modified Tinker source code to support one-dimensional position restraints.
"params.tar.gz" contains a description of the force field modifications.

To use "mod2", add the following lines to the key file.

#compatible with amoebabio18.prm
polarize      5          1.4500     0.3900      3
polarize     11          1.4500     0.3900      9
polarize      3          1.7500     0.3900      1    5    7   50  225  227
polarize      9          1.7500     0.3900      1    7   11   50  225  227

 

Files

Files (35.9 MB)

Name Size Download all
md5:fe3e2cb2b10bff625c36c1d9857ff269
33.1 MB Download
md5:4721f20009961bd24b309d17639f42f0
2.7 MB Download
md5:d7d8a82269fe0fa4d0197db29e26bcdb
363 Bytes Download

Additional details

Related works

Is supplement to
10.1039/d1sc01887f (DOI)

Funding

National Institutes of Health
Specificity and Selectivity in Protein-Ion Binding 5R01GM114237-04
National Institutes of Health
DEVELOPMENT OF A NEXT-GENERATION NUCLEIC ACID FORCE FIELD 5R01GM106137-03

References

  • Jing et al. Chemical Science, 2021. DOI: 10.1039/d1sc01887f