Project deliverable Open Access

B1MG D3.1 - Quality metrics for sequencing

Gut, Ivo; Estelles, Lucia; Cuppen, Edwin; Wirta, Valtteri; Hovig, Eivind; Volkert, Pim; Matthijs, Gert

Next Generation Sequencing (NGS) is becoming increasingly used in clinical settings for the genomic analysis of germline and cancer samples. Hence, there is a need to establish guidelines that cover the minimum quality requirements for the generation of whole genome sequencing (WGS) and whole exome sequencing (WES) data. NGS pipelines are comprised of several elements, all of which contribute to the end quality of the result, from the reception of the samples to delivery of the outcomes. For this reason, quality control (QC) steps should be incorporated into the workflow to ensure that the data is fit for use, and its usage poses no risk to the patient.

Files (1.4 MB)
Name Size
B1MG D3.1 - Quality metrics for sequencing.pdf
md5:ce4e24a0df6727b461e9c5386a826a3f
1.4 MB Download
21
15
views
downloads
All versions This version
Views 2121
Downloads 1515
Data volume 20.3 MB20.3 MB
Unique views 2020
Unique downloads 1515

Share

Cite as