Published March 21, 2016 | Version v1
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Model of striatum medium spiny neurons

  • 1. Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

Description

This is a subcellular signaling kinetic model of the striatal medium spiny neuron (msn) by Nair et al., (2015). It simulates the dopamine and acetylcholine dependent activation of cAMP/PKA in the dopamine type 1 receptor positive msn of the direct pathway. The full model description can be found in the BioModels database (https://www.ebi.ac.uk/biomodels-main/ Model id: MODEL1502200000).

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Additional details

References

  • doi: 10.1523/JNEUROSCI.0730-15.2015