Published March 15, 2016 | Version v1

Heatmaps of orthology and protein domain preservation in RNA Processing complexes throughout the fungal kingdom

Description

An analysis of the presence/absence of orthologues for Fungal RNA Processing protein complexes, and the presence/absence of the known PFAM protein domains within each protein within these complexes in the organism's proteome.  

Each image represents one RNA Processing protein complex.

Orthology (far left panel in each image) is relative to Yeast, and taken from a query against the EnsEMBL orthology database (black = no orthologue; red = orthologue).  

Each orthologue was then queried for its PFAM domains, and the non-redundant set of PFAM domains representing each set of orthologous proteins, spanning all species, was then scanned against the complete proteome of each species.  The resulting heatmap indicates the presence or absence of that PFAM domain anywhere in the proteome of that species.  (black = absent; red = 1 copy; grey->blue = more than one copy)

Notes

There is a (machine readable) FAIR Data Descriptor for this dataset at https://zenodo.org/record/161719. This contains the URLs for all species and PFAM domains, ontological terms related to each image within the dataset, and EDAM descriptors of the experiment.

Files

final.CCR4NOT_complex.png

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Additional details

Related works

Is referenced by
10.5281/zenodo.161719 (DOI)