Published May 28, 2020 | Version v.1.
Journal article Open

Care of patients with non-small-cell lung cancer stage III - The Central European real-world experience.

  • 1. 1st Faculty of Medicine of Charles University in Prague, Prague Czech Republic
  • 2. Department of Medicine I, Medical University of Vienna, Vienna, Austria
  • 3. Institute of Biostatistic and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • 4. Clinic for Pulmonology, Clinical Centre of Serbia, Belgrade, Serbia
  • 5. Institute of Oncology, Ljubljana, Slovenia
  • 6. National Koranyi Institute of TB and Pulmonology, Budapest, Hungary
  • 7. Pauls Stradins Clinical University Hospital, Riga, Latvia
  • 8. Comprehensive Oncology Center, Nový Jičín, Liberec Czech Republic
  • 9. Comprehensive Oncology Center, Liberec, Czech Republic
  • 10. Clinic for Pneumology & Tuberculosis, Faculty of Medicine, Palacký University, Olomouc, Czech Republic
  • 11. Clinic for Pneumology & Tuberculosis, Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • 12. Hospital of LUHS Kauno Klinikos, Kauno, Lithuania
  • 13. Thomayer Hospital, Prague, Czech Republic
  • 14. Department of Pulmonology, University Hospital Motol, Prague, Czech Republic
  • 15. Comprehensive Oncology Center and Multiscan, Pardubice, Czech Republic
  • 16. Department of Radiotherapy, Medical University of Vienna, Vienna, Austria
  • 17. Department of Thoracic Surgery, Semmelweis University, Budapest, Hungary
  • 18. Institute for Oncology and Radiology of Serbia, Belgrade, Serbia

Description

Background. Endometrial cancer represents a high health burden in Slovenia and worldwide. The incidence is increasing due to risk factors of lifestyle and behavior such as obesity, smoking, estrogen exposure and aging of the population. In many cases, endometrial cancer is diagnosed at an early stage due to obvious signs and symptoms. The standard treatment is surgery with or without adjuvant therapy, depending on the stage of the disease and the risk of recurrence. However, the treatment modalities have changed in recent decades, considerably in the extent of lymphadenectomy.

Conclusions. The gold standard of treatment of EC is surgery, which can be an only treatment modality in the early stages low grade tumours. In recent years, a minimally invasive approach with SNB has been proposed. If EC is in advance stage, high-risk hystology or high grade,  adjuvant therapy is recomended, radiotherapy, chemotherapy or a combination of both is recommended.

Notes

The project was funded by AstraZeneca for logistical and medical writing support.

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Is identical to
32463394 (PMID)
www.ncbi.nlm.nih.gov/pmc/articles/PMC7276648/ (Handle)
Is part of
1581-3207 (ISSN)