Published May 4, 2021 | Version v1

Structural Bioinformatic and Genomic Analyses of RORg Interacting with Cognate Response Elements

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Description

This is a series of scripts or script outputs to accompany a scientific publication examining the DNA-recognition of the nuclear receptor called RORγ. Contained within are scripts used to evaluate genomic distributions of specific DNA-sequences and their functional importance. This deposition also contains scripts used to generate integrative structural models of RORγ on cognate response elements. 

Files

Structural Analysis of RORg RORE SRC3 Complexes Manuscript.zip

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Additional details

Funding

National Institutes of Health
Determining the structural basis for ligand-mediated ROR? activation 5F31GM126842-02
National Institutes of Health
Optimization of RORgamma-specific agonists as immune activators for a new immunotherapy approach for cancer 5R01CA206493-03