OBSERVATIONAL STUDY TO EVALUATE THE RISK AND PREVALENCE OF CARDIOVASCULAR DISEASES AND RENAL IMPAIRMENT IN PATIENTS WITH PSORIASIS

Background: Cardiovascular disease (CVD) - the leading cause of death globally. In many countries, CVD is the major disease in population, including smoking, hypertension, and elevated serum cholesterol, are now improving, and age-specific mortality rates are declining So we are assessing the risk of Cardiovascular diseases and renal impairment in psoriasis which is a inflammatory disorder.

Aim: To assess the CVD risk, RI risk and QOL in patients with psoriasis and to know the prevalence of psoriasis.

Methodology: Ambispective observational study was carried out in Government General Hospital, Guntur. Patients who satisfy inclusion criteria were included in the study after obtaining informed consent. QRISK 3 is uses to assess the risk of cardiovascular disease in patients and Qkidney scale is used to assess the risk of renal impairment in the patients. By using SF36 quality of life is assessed.

Results: We observed that, with increase in disease duration, there is an increase in inflammation there is an increase in cardiovascular disease risk We revealed that, Psoriasis, is not initiating the renal impairment risk in cases, because of inflammation that is caused by this disease leads to renal impairment risk. Cardiovascular diseases is 28.64%, prevalent in psoriasis disease respectively. Renal impairment is 5.94%, prevalent in psoriasis.

Conclusion: Based on the results obtained our study strongly concludes that there is a cardiovascular risk and renal impairment risk in people suffering with psoriasis and there is a risk of disease, with increase in disease duration, there is a decrease in quality of life in the patients.