Published April 20, 2021 | Version v1.0
Software Open

Enhanced Ca2+ signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1h M1560V/+)

Creators

  • 1. Department of Nephrology, Charité–Universitätsmedizin Berlin, 10115 Berlin, Germany
  • 2. Department of Genetics, Yale University School of Medicine, New Haven, CT 06519
  • 3. Max Delbruck Center for Molecular Medicine, Helmholtz Association of German Research Centers, 13125 Berlin, Germany
  • 4. Department of Physiology, Universitätsmedizin Greifswald, 17475 Greifswald, Germany
  • 5. Laboratory of Human Genetics and Genomics, The Rockefeller University, New York, NY 10065
  • 6. Section of Comparative Medicine, Yale Genome Editing Center, Yale University School of Medicine, New Haven, CT 06519

Description

This repository contains the code that was used to analyze blood pressure data included in Seidel et al., PNAS, 2021 (https://doi.org/10.1073/pnas.2014876118), as well as the blood pressure data (.r file). For further information, please see the "Materials and Methods" section of the publication as well as the references cited therein and the README file at this repository.

Notes

This work was supported by the Fritz Thyssen Stiftung Grant 10.16.1.027MN (to U.I.S.); the Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen Rückkehrprogramm and Junges Kolleg grants (both to U.I.S.); the Stiftung Charité BIH Johanna Quandt Professorship (U.I.S.); the Deutsche Forschungsgemeinschaft Grant SFB 1365 (to S.K.F., D.N.M., and U.I.S.) and STO 1260/1-1 (to G.S.); the DZHK (German Centre for Cardiovascular Research) (S.K.F.); and the BMBF (German Ministry of Education and Research) (S.K.F.).

Files

erseidel/Cacna1h-mice-v1.0.zip

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