Journal article Open Access

A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro

Cheng; Porritt; Noval Rivas; Krieger; Ozdemir; Garcia Jr; Arumugaswami; Fries; Arditi; Bahar

Representative coordinate files in PDB format (homology models and docking models) from the work which first appeared on bioRxiv and later accepted for publication by Structure.

A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro

Mary Hongying Cheng, Rebecca A. Porritt, Magali Noval Rivas, James M Krieger, Asli Beyza Ozdemir, Gustavo Garcia Jr, Vaithilingaraja Arumugaswami, Bettina C. Fries, Moshe Arditi and Ivet Bahar

bioRxiv 2020 Nov 24;2020.11.24.395079. doi: 10.1101/2020.11.24.395079. Preprint

https://pubmed.ncbi.nlm.nih.gov/33269352/

Six PDB files are uploaded

(1) Homology model of human TMPRSS2.

(2) Docking model of SARS-CoV-2 Spike bound to TMPRSS2.

(3) Docking model of SARS-CoV-2 Spike bound to furin.

(4) Docking model of antibody 6D3 bound to SARS-CoV-2 spike in one up state.

(5) Docking model of antibody 6D3 bound to SARS-CoV-2 Spike in down states.

(6) Docking model of antibody 6D3 bound to HCoV-OC43 Spike in down states.

Files (14.7 MB)
Name Size
Antibody 6D3 bound to HCoV OC43 on 6NZK.pdb
md5:ed8a388a762757b9dcc70a9b67fcc090
3.0 MB Download
Antibody 6D3 bound to SARS-CoV-2 Spike in down states.pdb
md5:cc5df9dbe0ec9f3c65553930e73a41a2
2.9 MB Download
Antibody 6D3 bound to SARS-CoV-2 Spike on 6VSB.pdb
md5:59f6d24ae662200bde9222f767de1b66
2.8 MB Download
Homology model Human_TMPRSS2_on_PDB5CE1.pdb
md5:673472c80d8f2184d6abee47f81f6797
155.5 kB Download
SARS-CoV-2 spike_TMPRSS2_refined_model.pdb
md5:1b080ef64ebaf91d6f38d810e9fb190c
2.8 MB Download
SARS-CoV2 spike_furin_refined_model.pdb
md5:8ca6dda40c735bb6472044b8f6702e6e
3.0 MB Download
51
9
views
downloads
All versions This version
Views 5151
Downloads 99
Data volume 21.3 MB21.3 MB
Unique views 4646
Unique downloads 88

Share

Cite as