A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Creators
- 1. University of Pittsburgh
- 2. Cedars-Sinai Medical Center
- 3. UCLA
- 4. Stony Brook University Hospital
Description
Representative coordinate files in PDB format (homology models and docking models) from the work which first appeared on bioRxiv and later accepted for publication by Structure.
A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Mary Hongying Cheng, Rebecca A. Porritt, Magali Noval Rivas, James M Krieger, Asli Beyza Ozdemir, Gustavo Garcia Jr, Vaithilingaraja Arumugaswami, Bettina C. Fries, Moshe Arditi and Ivet Bahar
bioRxiv 2020 Nov 24;2020.11.24.395079. doi: 10.1101/2020.11.24.395079. Preprint
https://pubmed.ncbi.nlm.nih.gov/33269352/
Six PDB files are uploaded
(1) Homology model of human TMPRSS2.
(2) Docking model of SARS-CoV-2 Spike bound to TMPRSS2.
(3) Docking model of SARS-CoV-2 Spike bound to furin.
(4) Docking model of antibody 6D3 bound to SARS-CoV-2 spike in one up state.
(5) Docking model of antibody 6D3 bound to SARS-CoV-2 Spike in down states.
(6) Docking model of antibody 6D3 bound to HCoV-OC43 Spike in down states.
Files
Files
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