Published November 4, 2020
| Version 1
Journal article
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Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
Creators
- Filbin, Michael1
- Mehta, Arnav1
- Schneider, Alexis2
- Kays, Kyle1
- Guess, Jamey3
- Gentili, Matteo2
- Fenyves, Bank1
- Charland, Nicole1
- Gonye, Anna1
- Gushterova, Irena1
- Khanna, Hargun1
- LaSalle, Thomas1
- Lavin-Parsons, Kendall1
- Lilly, Brendan1
- Lodenstein, Carl1
- Manakongtreecheep, Kasidet1
- Margolin, Justin1
- McKaig, Brenna1
- Rojas-Lopez, Maricarmen1
- Russo, Brian1
- Sharma, Nihaarika1
- Tantivit, Jessica1
- Thomas, Molly1
- Gerszten, Robert4
- Heimberg, Graham2
- Hoover, Paul2
- Lieb, David2
- Lin, Brian1
- Ngo, Debby4
- Pelka, Karin2
- Reyes, Miguel2
- Smillie, Christopher2
- Waghray, Avinash1
- Wood, Thomas1
- Zajac, Amanda1
- Jennings, Lori5
- Grundberg, Ida3
- Bhattacharyya, Roby1
- Parry, Blair1
- Villani, Alexandra-Chloe1
- Sade-Feldman, Moshe1
- Hacohen, Nir1
- Goldberg, Marcia1
- 1. MGH
- 2. Broad Institute of MIT and Harvard
- 3. Olink proteomics
- 4. BIDMC
- 5. Novartis
Description
Plasma proteomic analysis of COVID19-positive patients presenting to the ED at MGH. The dataset includes 384 COVID19-positive and COVID19-negative control patients over serial timepoints (day 0, 3 and 7). The data includes analysis of plasma by the SomaScan assay. Additional data using the Olink Proteomics assay can be found here: https://www.olink.com/mgh-covid-study/.
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