Supplementary Information for "Diversification of 4ʹ-Methylated Nucleosides by Nucleoside Phosphorylases"

This is the external Supplementary Information for our publication "Diversification of 4ʹ-Methylated Nucleosides by Nucleoside Phosphorylases".

The .pdf file contains the Supplementary Information: author contributions, experimental procedures and supplementary items, among others.

The .zip file contains the raw data and metadata for all items (supplementary and main text) as well as the calculations. This includes UV, HPLC, HRMS, NMR and crystallographic data as well as docking results.

The Python code used for spectral unmixing is available on this platform (https://doi.org/10.5281/zenodo.3243376) and has been described in our previous publications (https://doi.org/10.3390/mps2030060, https://doi.org/10.5281/zenodo.3333469, https://doi.org/10.1002/cbic.202000204, https://doi.org/10.5281/zenodo.3723806). Further applications of this method can be found in our recent articles in Adv. Synth. Catal. (https://doi.org/10.1002/adsc.201901230) and its supporting material (https://doi.org/10.5281/zenodo.3568858) and in ChemBioChem (https://doi.org/10.1002/cbic.202000679) and its supporting material on this platform (https://doi.org/10.5281/zenodo.4284188). The equilibrium shift method employed for the half-life determination of the methylated sugar phosphate is described in detail in our article in ChemPhysChem (https://doi.org/10.1002/cphc.202000901).