Transmission Electron Microscopy Tilt Series Data of Chondrocyte Primary Cilia in situ

Overlooked for decades as an evolutionary vestigial organelle, the primary cilium has recently become the focus of intensive investigations into understanding of the physical structure and processes of eukaryote cell function. The cilium is central to various pathways and modalities for signalling, allowing centrosomal processing and regulation of cellular and organelle function. The enigmatic process of their nanoscale ciliogenesis and sensory function at present remain poorly understood. Dysfunction of their normal function or component proteins correlates with a wide spectrum of diseases, or ciliopathies, which express as developmental disorders and pathologies. This paper describes transmission electron microscope acquisitions of  both single and dual axis tilt series images of  chick embryo sternal  cartilage primary cilia