Published July 19, 2019
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Raw data related to: Loss of Non-Apoptotic Role of Caspase-3 in the PINK1 Mouse Model of Parkinson's Disease
Authors/Creators
- 1. Laboratory of Neurophysiology and Plasticity, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy
Description
Fig. 6A,B,C – Effect of caspase-3 activation on synaptic responses to sustained electrical stimulation in PINK1-/- MSNs.
(A) Time-course of synaptic responses to sustained stimulation (30 Hz, 30 s) in PINK1+/+ MSNs. Current peak amplitudes are reported as mean SEM. In the inset, the first and last EPSC from a representative experiment are shown. (B) Time course of synaptic responses in PINK1+/- MSNs shows a similar response to sustained stimulation. (C) In PINK-/- MSNs, we observed faster depression kinetics after the 12th stimulus.
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Related works
- Is supplement to
- Journal article: 10.3390/ijms20143407 (DOI)