Dataset Open Access

Data for Developmental cell programs are co-opted in inflammatory skin disease - filtered, annotated anndata object

Gary Reynolds; Peter Vegh; James Fletcher; Elizabeth Poyner; Muzlifah Haniffa; Fiona Watt; Sarah Teichmann

Dataset to accompany BioRxiv preprint "Poised cell circuits in human skin are activated in disease" (https://www.biorxiv.org/content/10.1101/2020.11.05.369363v1). Data in AnnData (h5ad) format. Preprocessed to exclude doublets and low quality cells (<200 genes and >20% mitochondrial content).

Healthy.h5ad includes neighborhood graph and UMAP coordinates and annotation from the manuscript in figure 1B.

Full dataset with annotation ("combined") in obs.

This has been updated - the previous version had multiple old annotations that are no longer in use,
Files (5.7 GB)
Name Size
completeSS2.RDS
md5:d5569f1cd14cc3b4357c2bc4a301cd39
87.3 MB Download
fetal_submission.h5ad
md5:43fff9730eebffa6da33d434957a7b20
533.2 MB Download
healthy.h5ad
md5:9aa6715d272bab7b7169d8fee848ca17
1.2 GB Download
submission_210120.h5ad
md5:0f76145e788f04e38750e5679c385b81
3.9 GB Download
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