Published February 3, 2021 | Version v1
Dataset Open

Generation, characterization and drug sensitivities of twelve patient-derived IDH1 mutant glioma cell cultures

  • 1. Department of Neurosurgery, Brain Tumor Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, 3015 GN, The Netherlands
  • 2. Department of Neurology, Brain Tumor Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, 3015 GN, The Netherlands
  • 3. Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, Zuid-Holland, 3015 GN, The Netherlands
  • 4. Department of Biology, Faculty of Natural Sciences, Universidad del Rosario, Bogotá, Colombia
  • 5. Information Technologies for Translational Medicine (ITTM), Esch-Sur-Alzette, 4362, Luxembourg (RTCY)
  • 6. Metabolic Unit, Department of Clinical Chemistry, Amsterdam University Medical Center, Noord-Holland, 1081 HV, The Netherlands
  • 7. Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, 3015 GN, The Netherlands

Description

RNA-seq data of glioma samples and their matched primary cultures. Cultures were exposed to the IDH mutant-specific inhibitor AGI-5198 or DMSO control. 

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French2_INDEL_80.slt.vcf.full_annotation.txt

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Additional details

Funding

European Commission
GLIOTRAIN - Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics 766069