PREGNANCY OUTCOMES OF COVID-19 POSITIVE PATIENTS; A SYSTEMATIC REVIEW OF LITERATURE

Objective: Coronavirus disease 2019 became a pandemic and had many adverse effect on whole world this review is to estimate the pregnancy outcomes of Covid-19 positive patients and its effect on neonates.

Study Design: In this study, digital databases including PubMed, EMBASE and Google scholar were searched from January 2020 to August 2020. All relevant studies on Pregnancy and COVID-19 were reviewed and systematic reviews, meta-analysis, case studies were excluded. Prospective, Observational, Retrospective Cohorts and a Case series is included in this review.

Results: A total of 647 covid-19 positive pregnant women in their 2^nd and 3^rd trimester and 439 neonates were analysed from 9 selected studies. Maternal and neonatal mortality rate is 0. No major deformity is seen in neonates However, factors like low birth weight, pre-term delivery, neonatal pneumonia and increased C-section rate is observed.

Conclusion: Effects of covid-19 varies in all studies because of study design, duration, place, race and study population. Only 3% neonates were tested positive for Covid-19. Rate of C-section is highest in Chinese population (97%). No neonatal asphyxia, Fetal demise or acidosis seen.

Key Words: Covid-19, Severe Acute Respiratory Syndrome Coronavirus 2 Infection, lymphopenia, vertical transmission, preterm delivery, Neonatal pneumonia, Cesarean section, Middle Eastern Respiratory Syndrome.