Journal article Open Access

STUDY TO KNOW THE COMPARISON OF LUNG FUNCTION VARIATIONS AMONG ANEMIC AND NON-ANEMIC ADULTS

1Dr Aneela Latif, 2Dr Maria Liaqat, Dr Fareeha Saani Farooqi

Objective: To find the correlation that exists between blood hemoglobin/ serum iron indices and lung function tests. To compare changes in lung functions amongst the anemic and non-anemic adults.

Study Design: Case control study.

Place and Duration of Study: This study was conducted at the Jinnah Hospital Lahore from March 2020 to September 2020.

Materials and Methods: 100 males and 100 female diagnosed iron deficient anemic adults in range of 18-45 years and with no co-morbid respiratory and cardiac diseases were included. Inclusion criteria included iron deficient anemic adults with no acute emergency states and no chest and back area deformities. Blood samples were reanalyzed for blood hemoglobin (Hb) by automated cell analyzer and anemia were rechecked for confirmation of iron deficiency anemia (IDA) by doing further tests like serum iron, serum ferritin, serum Total Iron Binding Capacity (TIBC) levels by Enzyme Linked Immunosorbent Assay (ELISA). Digital spirometer was used to perform Pulmonary Function Tests (PFTs) which includes Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1st second of FVC (FEV1) in all anemic patients and lung functions were compared with lung functions of non-anemic healthy individuals.

Results: The FVC and FEV1 in male and female cases were significantly reduced(p<0.05) as compared to that in male and female controls respectively. Whereas the FEV1/FVC ratio was significantly increased (p<0.05) in male and female cases. Restrictive lung changes were observed in male and female cases.

Conclusion: In the present study positive association was observed between blood Hb/serum iron indices and lung functions in anemic patientsThe results showed restrictive lung function changes in anemic subjectsWhile no abnormal lung function changes were found in non-anemic healthy participants.

Key Words: Hemoglobin, Iron Deficiency Anemia, Pulmonary Function Tests.

Files (713.9 kB)
Name Size
398.med 102 final.pdf
md5:3558ed03a462f22de8e882a5e93d0ddb
713.9 kB Download
5
2
views
downloads
All versions This version
Views 55
Downloads 22
Data volume 1.4 MB1.4 MB
Unique views 55
Unique downloads 22

Share

Cite as