Published September 18, 2014
| Version v1
Dataset
Open
HAND2 Targets Define a Network of Transcriptional Regulators that Compartmentalize the Early Limb Bud Mesenchyme
Description
Highlights
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ChIP-seq identifies the CRMs bound by endogenous HAND2 in embryos and limb buds
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HAND2 controls key transcriptional regulators acting upstream of SHH in limb buds
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These transcriptional circuits define proximal, anterior, and posterior identities
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HAND2 establishes anterior and posterior compartments by regulating Gli3 and Tbx3
Files
Files
(137.1 MB)
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md5:249a2923b6254766c31a290bfd1422c9
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137.1 MB | Download |