Dataset related to article: "Time Course of Autonomic Symptoms in Postural Orthostatic Tachycardia Syndrome (POTS) Patients: Two-Year Follow-Up Results
Authors/Creators
- 1. Humanitas Clinical and Research Center – IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy
- 2. Department of Biomedical Sciences for Health, University of Milan, 20122 Milan, Italy
- 3. Departamento de Kinesiología, Universidad Católica del Maule, 3605 Talca, Chile
- 4. Humanitas Clinical and Research Center – IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy AND Humanitas University, Department of Biomedical Sciences, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele – Milan, Italy
Description
This record contains data related to article "Time Course of Autonomic Symptoms in Postural Orthostatic Tachycardia Syndrome (POTS) Patients: Two-Year Follow-Up Results"
Postural orthostatic tachycardia syndrome (POTS) is a multifactorial condition capable of
chronically reducing the quality of life and the work ability of patients. The study aim was to assess
the burden of autonomic symptoms in a cohort of POTS patients over 2 years. Patients’ clinical profiles
were assessed by the 31-item Composite Autonomic Symptom Score questionnaire (COMPASS 31)
and a visual analog scale (VAS). One-way ANOVA for repeated measures followed by Dunnett’s
post-hoc test were used to compare symptoms at baseline and at 1 and 2 years. Out of 42 enrolled
patients, 25 had a 1-year follow-up and 12 had a 2-year follow-up. At baseline, the reported burden
of autonomic symptoms was high (overall COMPASS 31 = 49.9 14.3 /100). Main complaints were
related to orthostatic intolerance according to both COMPASS 31 and VAS. Fourteen patients were
rendered inactive because of symptoms. At 1-year follow-up, a statistically significant improvement
in pupillomotor function and overall score was detected by the COMPASS 31. These findings were
confirmed at 2 years, together with a significant reduction in quality of life impairment, assessed
by VAS. However, these improvements did not change patients’ occupational status. Awareness of
POTS diagnosis, patient monitoring, and tailored therapies can help to improve patients’ condition.
Notes
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Additional details
Related works
- Is supplement to
- 10.3390/ijerph17165872 (DOI)