Published November 27, 2014 | Version v1
Journal article Open

Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid

Authors/Creators

  • 1. Department of Chemistry, Faculty of Physics and Chemistry, Alzahra University, Vanak, Tehran, Iran.
  • 2. Faculty of Chemistry, Bu-Ali Sina University, P.O. Box 6517838683, Hamedan, Iran.
  • 3. Catalysis and Peptide Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.
  • 4. Pishro Parsian Company, 11th floor, No. 1917, Amir Bldg, above the four way the Jalal alahmad, North Kargar Ave, 1439713134 Tehran, Iran

Description

A highly efficient protocol for the synthesis of 1,2,3,4-tetrahydropyridines in the presence of nano-sphere silica sulfuric acid (NS-SSA) was used for good yields by one-pot multicomponent reaction (MCRs). The reagent nano-sphere silica sulfuric acid (NS-SSA) has several advantages, such as easy workup, nontoxicity, convenience and high yields of products.

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