X-ray structure ensemble refinement of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) (space group P21212)

X-ray structure ensemble refinement of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) (space group P21212). Raw diffraction images are available on Zenodo: 10.5281/zenodo.4086066. A single conformer model was deposited in the Protein Data Bank under accession code 7AV8. Refinement was carried out with phenix.ensemble_refinement and the repository contains all input and output files:

Input:

• mx8421v63_xPHIPAx1521_free.mtz
• refine9.pdb

Output:

• PHIPA-P21212_ensemble_refinement_ensemble.geo
• PHIPA-P21212_ensemble_refinement_ensemble.pdb
• PHIPA-P21212_ensemble_refinement_ensemble.mtz
• PHIPA-P21212_ensemble_refinement_ensemble.log